Determination of Efficacy of Anvirzel in 37 Established Cancer Cell Lines

The present study investigates the efficacy of AnvirzelTM, an extract of Nerium oleander, in more than 35 different human cancer cell lines, including all the types of tumours. Assays that have been used in order to measure the efficacy of AnvirzelTM in 24, 48 and 72h of incubation in 37 different cancer cell lines, were viability assays [Methyl-Tetrazolium dye (MTT), Crystal violet staining (CVE) and SulfoRodhamine B (SRB)]. In colon, lung, uterus and breast cancer cell lines, reduction of the null has been shown, up to 70% by type. All studies to date have demonstrated the efficacy of AnvirzelTM in individual cancers, such as prostate, pancreatic and myeloma cell lines. The present study demonstrates that this drug has a wider field of action, also in other cancer cell lines. It would be preferable to conduct studies concluding the interaction between AnvirzelTM and other drugs that are used already for the treatment of these cancers.